SCHEMBL25233333

SCHEMBL25233333

O=C(O)[C@@H]1CC2CC=CC=C2CN1C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.42
FABP7 O15540 2/20 0.42
KMT2A Q03164 2/20 0.35
EPHX2 P34913 1/20 0.34
DPP8 Q6V1X1 1/20 0.33
DPP9 Q86TI2 1/20 0.33
MDM4 O15151 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
CASP3 P42574 1/20 0.32
PIN1 Q13526 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8351536 1.00 FABP5 (0.42) FABP5FABP7KMT2AEPHX2DPP8
SCHEMBL5157204 0.78 FABP5 (0.54) FABP5FABP7KMT2AEPHX2DPP8
SCHEMBL30510279 0.78 FABP5 (0.54) FABP5FABP7KMT2AEPHX2DPP8
SCHEMBL1830867 0.78 FABP5 (0.54) FABP5FABP7KMT2AEPHX2DPP8
SCHEMBL3576113 0.78 FABP5 (0.54) FABP5FABP7KMT2AEPHX2DPP8
SCHEMBL6558488 0.78 FABP5 (0.54) FABP5FABP7KMT2AEPHX2DPP8
SCHEMBL30510365 0.78 FABP5 (0.54) FABP5FABP7KMT2AEPHX2DPP8
SCHEMBL30510380 0.78 FABP5 (0.54) FABP5FABP7KMT2AEPHX2DPP8
SCHEMBL7147050 0.76 FABP5 (0.45) FABP5FABP7KMT2AEPHX2DPP8
SCHEMBL14393126 0.74 FABP5 (0.46) FABP5FABP7KMT2AEPHX2MDM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823223-A Apelin peptide energy macrocycle and application thereof SOCPRA健康与人文科学有限公司 2025-04-15 CN claimed
EP-4448547-A1 APELINERGIC MACROCYCLES AND USES THEREOF Socpra Sciences Santé Et Humaines S.E.C. (CA) 2024-10-23 EP claimed
CN-118829646-A Apelin peptide energy macrocycle and application thereof SOCPRA健康与人文科学有限公司 2024-10-22 CN claimed
US-20240343761-A1 APELINERGIC MACROCYCLES AND USES THEREOF SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2024-10-17 US claimed
WO-2023108291-A9 APELINERGIC MACROCYCLES AND USES THEREOF SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2023-09-28 WO claimed
WO-2023108291-A1 APELINERGIC MACROCYCLES AND USES THEREOF SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2023-06-22 WO claimed
CN-119823223-A Apelin peptide energy macrocycle and application thereof SOCPRA健康与人文科学有限公司 2025-04-15 CN disclosed
EP-4448547-A1 APELINERGIC MACROCYCLES AND USES THEREOF Socpra Sciences Santé Et Humaines S.E.C. (CA) 2024-10-23 EP disclosed
CN-118829646-A Apelin peptide energy macrocycle and application thereof SOCPRA健康与人文科学有限公司 2024-10-22 CN disclosed
US-20240343761-A1 APELINERGIC MACROCYCLES AND USES THEREOF SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2024-10-17 US disclosed
WO-2024011333-A1 METHOD OF TREATING SKELETAL MUSCLE STEM CELL PATHOLOGIC DYSFUNCTION SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2024-01-18 WO disclosed
WO-2023108291-A9 APELINERGIC MACROCYCLES AND USES THEREOF SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2023-09-28 WO disclosed
WO-2023108291-A1 APELINERGIC MACROCYCLES AND USES THEREOF SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2023-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240343761-A1 APELINERGIC MACROCYCLES AND USES THEREOF APLNR, AP3D1, AP3B1 FABP5 1240/4885FABP7 336/4885KMT2A 3553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.