Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 6/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.46 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30460145 | 1.00 | SLCO1B1 (0.46) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL25691468 | 0.93 | SLCO1B1 (0.39) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL19715479 | 0.83 | SLCO1B1 (0.66) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL30544898 | 0.82 | NPC1 (0.36) | — | |
| SCHEMBL25238670 | 0.82 | NPC1 (0.36) | — | |
| SCHEMBL19715709 | 0.81 | SLCO1B1 (0.66) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL23671232 | 0.81 | SLCO1B1 (0.54) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL30460148 | 0.80 | SLCO1B1 (0.48) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL25687957 | 0.80 | SLCO1B1 (0.48) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL25232876 | 0.80 | KDM4C (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109878-A1 | TRIAZASPIRO LPAR1 ANTAGONIST AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-06-22 | — | — | WO | disclosed |