Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30460030 | 1.00 | KDM4C (0.33) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL25278645 | 0.88 | KDM4C (0.35) | KDM4CNPC1RAB9A | |
| SCHEMBL25238670 | 0.88 | NPC1 (0.36) | KDM4CNPC1RAB9AL3MBTL1 | |
| SCHEMBL30544898 | 0.88 | NPC1 (0.36) | KDM4CNPC1RAB9AL3MBTL1 | |
| SCHEMBL25239936 | 0.88 | GABRA5 (0.33) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL25278970 | 0.83 | ABCB11 (0.34) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL25231360 | 0.81 | SLCO1B1 (0.35) | KDM4CNPC1RAB9A | |
| SCHEMBL30460219 | 0.81 | KDM4C (0.34) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL30460092 | 0.80 | NPC1 (0.41) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL25235641 | 0.80 | SLCO1B1 (0.46) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640117-A | Triazole LPAR1 antagonists and uses thereof | 武汉人福创新药物研发中心有限公司 | 2023-08-25 | — | — | CN | disclosed |
| WO-2023109878-A1 | TRIAZASPIRO LPAR1 ANTAGONIST AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-06-22 | — | — | WO | disclosed |
| WO-2023109878-A1 | TRIAZASPIRO LPAR1 ANTAGONIST AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-06-22 | — | — | WO | disclosed |