Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | PLK1 | P53350 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | FDPS | P14324 | 1/20 | 0.57 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.56 |
| ▸ | TACR2 | P21452 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL413085 | 0.84 | TACR2 (0.78) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL856386 | 0.82 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL15452397 | 0.81 | NPC1 (0.73) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL14554263 | 0.80 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL2699064 | 0.80 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL12517074 | 0.80 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL1224584 | 0.80 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL856264 | 0.80 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL7784719 | 0.79 | PDCD1 (0.74) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL1353565 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203006-A1 | VANILLIN DERIVATIVE COMPOUNDS INDUCING SELECTIVE DEGRADATION OF PLK1 | UPPTHERA (KR) | 2023-06-29 | — | — | US | disclosed |
| US-20230203006-A1 | VANILLIN DERIVATIVE COMPOUNDS INDUCING SELECTIVE DEGRADATION OF PLK1 | UPPTHERA (KR) | 2023-06-29 | — | — | US | disclosed |
| US-20230203006-A1 | VANILLIN DERIVATIVE COMPOUNDS INDUCING SELECTIVE DEGRADATION OF PLK1 | UPPTHERA (KR) | 2023-06-29 | — | — | US | disclosed |
| CN-109651365-B | 3-methylpyrido [1,2-a ] pyrimidone derivative containing 1- ((4-substituted benzyl) oxy) and application thereof | 贵州大学 | 2021-11-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203006-A1 | VANILLIN DERIVATIVE COMPOUNDS INDUCING SELECTIVE DEGRADATION OF PLK1 | PLK1, NEDD4, BUB1 | ALDH1A1 2773/4885MEN1 2994/4885KMT2A 820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.