Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2525618 | 1.00 | ACHE (0.51) | ACHENAAAEPHX1TSHRLMNA | |
| SCHEMBL2530896 | 0.98 | ACHE (0.49) | ACHENAAAEPHX1LMNAALDH1A1 | |
| SCHEMBL18641869 | 0.95 | ACHE (0.50) | ACHENAAAEPHX1TSHRLMNA | |
| SCHEMBL2529452 | 0.93 | CA1 (0.42) | ACHENAAATSHRALDH1A1 | |
| SCHEMBL18098096 | 0.91 | CA1 (0.46) | ACHETSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL2529098 | 0.91 | ACHE (0.49) | ACHENAAAEPHX1TSHRLMNA | |
| SCHEMBL2525643 | 0.91 | ACHE (0.49) | ACHENAAAEPHX1TSHRLMNA | |
| SCHEMBL7223421 | 0.91 | NAAA (0.53) | ACHENAAAEPHX1TSHRLMNA | |
| SCHEMBL7217114 | 0.91 | NAAA (0.53) | ACHENAAAEPHX1TSHRLMNA | |
| SCHEMBL7217720 | 0.91 | NAAA (0.53) | ACHENAAAEPHX1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |