SCHEMBL2523726

SCHEMBL2523726

NCC(=O)N1CC(NC(=O)c2ccccc2)CC1C(N)=O

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 7/20 0.55
DPP4 P27487 2/20 0.46
ANPEP P15144 3/20 0.42
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
CTSK P43235 1/20 0.41
SMYD3 Q9H7B4 2/20 0.41
HPGD P15428 1/20 0.41
CARM1 Q86X55 1/20 0.41
PRMT6 Q96LA8 1/20 0.41
GRM5 P41594 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2399440 1.00 MMP2 (0.55) MMP2DPP4ANPEPCTSLCTSB
Danegaptide SCHEMBL20547963 0.91 MMP2 (0.56) MMP2ANPEPCTSLCTSBCTSK
Danegaptide SCHEMBL25694359 0.91 MMP2 (0.56) MMP2ANPEPCTSLCTSBCTSK
Danegaptide SCHEMBL2521817 0.91 MMP2 (0.56) MMP2ANPEPCTSLCTSBCTSK
Danegaptide SCHEMBL29094836 0.91 MMP2 (0.56) MMP2ANPEPCTSLCTSBCTSK
Danegaptide SCHEMBL2399763 0.91 MMP2 (0.56) MMP2ANPEPCTSLCTSBCTSK
Danegaptide SCHEMBL2399760 0.91 MMP2 (0.56) MMP2ANPEPCTSLCTSBCTSK
Danegaptide SCHEMBL2399462 0.90 MMP2 (0.55) MMP2ANPEPCTSLCTSBCTSK
Danegaptide SCHEMBL4040777 0.90 MMP2 (0.55) MMP2ANPEPCTSLCTSBCTSK
Danegaptide SCHEMBL4040780 0.90 MMP2 (0.55) MMP2ANPEPCTSLCTSBCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2386539-B1 4-Aminoproline derivatives useful as lysine mimetics ZEALAND PHARMA AS (DK) 2016-07-20 EP claimed
EP-1966130-B1 MODIFIED LYSINE-MIMETIC COMPOUNDS ZEALAND PHARMA AS (DK) 2013-12-11 EP claimed
US-20130225644-A1 MODIFIED LYSINE-MIMETIC COMPOUNDS ZEALAND PHARMA A/S (DK) 2013-08-29 US claimed
EP-2386539-A2 Modified lysine-mimetic compounds Zealand Pharma A/S (DK) 2011-11-16 EP claimed
US-D647202-S1 Bone marrow harvesting device WARSAW ORTHOPEDIC, INC. (US) 2011-10-18 US claimed
EP-1966130-A2 MODIFIED LYSINE-MIMETIC COMPOUNDS Zealand Pharma A/S (DK) 2008-09-10 EP claimed
WO-2007078990-A2 MODIFIED LYSINE-MIMETIC COMPOUNDS ZEALAND PHARMA A/S (DK) 2007-07-12 WO claimed
US-20070149460-A1 Modified lysine-mimetic compounds ZEALAND PHARMA A/S (DK) 2007-06-28 US claimed
EP-2386539-A2 Modified lysine-mimetic compounds Zealand Pharma A/S (DK) 2011-11-16 EP disclosed
US-D647202-S1 Bone marrow harvesting device WARSAW ORTHOPEDIC, INC. (US) 2011-10-18 US disclosed
EP-1966130-A2 MODIFIED LYSINE-MIMETIC COMPOUNDS Zealand Pharma A/S (DK) 2008-09-10 EP disclosed
WO-2007078990-A2 MODIFIED LYSINE-MIMETIC COMPOUNDS ZEALAND PHARMA A/S (DK) 2007-07-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130225644-A1 MODIFIED LYSINE-MIMETIC COMPOUNDS MYLK2, KCNN2, KCNN1 MMP2 1902/4885DPP4 370/4885ANPEP 491/4885
US-20070149460-A1 Modified lysine-mimetic compounds MYLK2, KCNN2, KCNN1 MMP2 1902/4885DPP4 370/4885ANPEP 491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.