Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.56 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.47 |
| ▸ | ANPEP | P15144 | 4/20 | 0.46 |
| ▸ | ACE | P12821 | 3/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Danegaptide SCHEMBL2521817 | 1.00 | MMP2 (0.56) | MMP2AGTR2ANPEPACECTSL | |
| Danegaptide SCHEMBL2399760 | 1.00 | MMP2 (0.56) | MMP2AGTR2ANPEPACECTSL | |
| Danegaptide SCHEMBL25694359 | 1.00 | MMP2 (0.56) | MMP2AGTR2ANPEPACECTSL | |
| Danegaptide SCHEMBL20547963 | 1.00 | MMP2 (0.56) | MMP2AGTR2ANPEPACECTSL | |
| Danegaptide SCHEMBL29094836 | 1.00 | MMP2 (0.56) | MMP2AGTR2ANPEPACECTSL | |
| Danegaptide SCHEMBL4040780 | 0.99 | MMP2 (0.55) | MMP2AGTR2ANPEPACECTSL | |
| Danegaptide SCHEMBL2399462 | 0.99 | MMP2 (0.55) | MMP2AGTR2ANPEPACECTSL | |
| Danegaptide SCHEMBL4040777 | 0.99 | MMP2 (0.55) | MMP2AGTR2ANPEPACECTSL | |
| Danegaptide SCHEMBL3103299 | 0.99 | MMP2 (0.55) | MMP2AGTR2ANPEPACECTSL | |
| Danegaptide SCHEMBL4037108 | 0.97 | MMP2 (0.54) | MMP2AGTR2ANPEPACECTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739309-A1 | DANEGAPTIDE FOR USE IN TREATING SYNUCLEINOPATHIES | Cambridge Enterprise Limited (GB) | 2026-05-13 | — | — | EP | claimed |
| WO-2025008625-A1 | DANEGAPTIDE FOR USE IN TREATING SYNUCLEINOPATHIES | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2025-01-09 | — | — | WO | claimed |
| EP-4452260-A1 | GAP JUNCTION MODULATORS AND THEIR USE FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION | Breye Therapeutics ApS (DK) | 2024-10-30 | — | — | EP | claimed |
| CN-118450892-A | Gap junction modulators and their use for the treatment of age-related macular degeneration | 布雷耶疗法有限公司 | 2024-08-06 | — | — | CN | claimed |
| CN-110709096-B | Cell gap junction communication regulator and application thereof in treatment of diabetic eye disease | 泽兰德制药公司 | 2023-10-31 | — | — | CN | claimed |
| WO-2023118366-A1 | GAP JUNCTION MODULATORS AND THEIR USE FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION | BREYE THERAPEUTICS APS (DK) | 2023-06-29 | — | — | WO | claimed |
| CN-112142823-B | ZP-1609 synthesis method | 深圳翰宇药业股份有限公司 | 2022-08-05 | — | — | CN | claimed |
| US-20130225644-A1 | MODIFIED LYSINE-MIMETIC COMPOUNDS | ZEALAND PHARMA A/S (DK) | 2013-08-29 | — | — | US | claimed |
| US-20130053344-A1 | SYNTHESIS OF PYRROLIDINE COMPOUNDS | ZEALAND PHARMA A/S (DK) | 2013-02-28 | — | — | US | claimed |
| US-20100249207-A1 | SYNTHESIS OF PYRROLIDINE COMPOUNDS | WYETH LLC (US) | 2010-09-30 | — | — | US | claimed |
| US-20080188545-A1 | (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid hydrochloride monohydrate; cardiovascular disease; osteoporosis; inflammation of airway epithelium; disorders of alveolar tissue; bladder incontinence; impaired hearing; endothelial lesions | ZEALAND PHARMA A/S (DK) | 2008-08-07 | — | — | US | claimed |
| US-20070149460-A1 | Modified lysine-mimetic compounds | ZEALAND PHARMA A/S (DK) | 2007-06-28 | — | — | US | claimed |
| EP-4739309-A1 | DANEGAPTIDE FOR USE IN TREATING SYNUCLEINOPATHIES | Cambridge Enterprise Limited (GB) | 2026-05-13 | — | — | EP | disclosed |
| EP-4739309-A1 | DANEGAPTIDE FOR USE IN TREATING SYNUCLEINOPATHIES | Cambridge Enterprise Limited (GB) | 2026-05-13 | — | — | EP | disclosed |
| US-12624002-B2 | Dimers for use in synthesis of peptidomimetics | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2026-05-12 | — | — | US | disclosed |
| US-12600699-B2 | Thiosemicarbazates and uses thereof | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2026-04-14 | — | — | US | disclosed |
| US-20080188545-A1 | (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid hydrochloride monohydrate; cardiovascular disease; osteoporosis; inflammation of airway epithelium; disorders of alveolar tissue; bladder incontinence; impaired hearing; endothelial lesions | ZEALAND PHARMA A/S (DK) | 2008-08-07 | — | — | US | disclosed |
| WO-2008079266-A2 | SYNTHESIS OF PYRROLIDINE COMPOUNDS | WYETH (US) | 2008-07-03 | — | — | WO | disclosed |
| WO-2007078990-A2 | MODIFIED LYSINE-MIMETIC COMPOUNDS | ZEALAND PHARMA A/S (DK) | 2007-07-12 | — | — | WO | disclosed |
| US-20070149460-A1 | Modified lysine-mimetic compounds | ZEALAND PHARMA A/S (DK) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12624002-B2 | Dimers for use in synthesis of peptidomimetics | GLUL, ARGLU1, ASNS | MMP2 2439/4885AGTR2 617/4885ANPEP 123/4885 |
| US-20130053344-A1 | SYNTHESIS OF PYRROLIDINE COMPOUNDS | CPS1, DHPS, DDC | MMP2 3894/4885AGTR2 1599/4885ANPEP 686/4885 |
| US-20080188545-A1 | (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid hydrochloride monohydrate; cardiovascular disease; osteoporosis; inflammation of airway epithelium; disorders of alveolar tissue; bladder incontinence; impaired hearing; endothelial lesions | GLS, COL2A1, MYOC | MMP2 970/4885AGTR2 61/4885ANPEP 347/4885 |
| US-20130225644-A1 | MODIFIED LYSINE-MIMETIC COMPOUNDS | MYLK2, KCNN2, KCNN1 | MMP2 1902/4885AGTR2 715/4885ANPEP 491/4885 |
| US-20100249207-A1 | SYNTHESIS OF PYRROLIDINE COMPOUNDS | CPS1, DHPS, DDC | MMP2 3894/4885AGTR2 1599/4885ANPEP 686/4885 |
| US-20070149460-A1 | Modified lysine-mimetic compounds | MYLK2, KCNN2, KCNN1 | MMP2 1902/4885AGTR2 715/4885ANPEP 491/4885 |
| US-12600699-B2 | Thiosemicarbazates and uses thereof | MET, THRB, ABAT | MMP2 1970/4885AGTR2 1134/4885ANPEP 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.