Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.60 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | CKS1B | P61024 | 1/20 | 0.48 |
| ▸ | SKP1 | P63208 | 1/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29319392 | 0.90 | ACHE (0.60) | ACHEDDB1CRBNGPR119CHRNA7 | |
| SCHEMBL7136906 | 0.90 | ACHE (0.63) | ACHEDDB1CRBNGPR119CHRNA7 | |
| SCHEMBL27213788 | 0.88 | ACHE (0.61) | ACHEDDB1CRBNGPR119CHRNA7 | |
| SCHEMBL30995427 | 0.88 | ACHE (0.61) | ACHEDDB1CRBNGPR119CHRNA7 | |
| SCHEMBL31706344 | 0.88 | ACHE (0.61) | ACHEDDB1CRBNGPR119CHRNA7 | |
| SCHEMBL29319390 | 0.87 | ACHE (0.57) | ACHEDDB1CRBNGPR119CHRNA7 | |
| SCHEMBL7161944 | 0.85 | ACHE (0.58) | ACHEDDB1CRBNGPR119CHRNA7 | |
| SCHEMBL15286547 | 0.85 | ACHE (0.62) | ACHEDDB1CRBNGPR119CHRNA7 | |
| SCHEMBL19015403 | 0.84 | ACHE (0.61) | ACHEDDB1CRBNGPR119CHRNA7 | |
| SCHEMBL30166226 | 0.84 | ACHE (0.61) | ACHEDDB1CRBNGPR119CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110843-A1 | HETEROBICYCLIC DERIVATIVES AS ITK INHIBITORS | ALMIRALL, S.A. (ES) | 2023-06-22 | — | — | WO | disclosed |