Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 11/20 | 0.80 |
| ▸ | ROCK1 | Q13464 | 10/20 | 0.67 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.62 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17311550 | 0.89 | ROCK2 (1.00) | ROCK2ROCK1NCOA1NCOA3ATM | |
| SCHEMBL24000656 | 0.85 | ROCK2 (0.66) | ROCK2ROCK1NCOA1NCOA3ATM | |
| SCHEMBL28917113 | 0.83 | ROCK2 (0.63) | ROCK2ROCK1NCOA1NCOA3ATM | |
| SCHEMBL30450065 | 0.82 | ROCK2 (0.62) | ROCK2ROCK1NCOA1NCOA3ATM | |
| SCHEMBL15878687 | 0.81 | ROCK1 (0.72) | ROCK2ROCK1ATMNPSR1 | |
| SCHEMBL17311646 | 0.80 | ROCK1 (1.00) | ROCK2ROCK1NCOA1NCOA3ATM | |
| SCHEMBL19675414 | 0.80 | ROCK1 (0.67) | ROCK2ROCK1NCOA1NCOA3ATM | |
| SCHEMBL25546668 | 0.80 | ENPP1 (0.62) | ROCK2ROCK1NCOA1NCOA3ATM | |
| SCHEMBL31014274 | 0.79 | ATM (0.67) | ROCK2ROCK1NCOA1NCOA3ATM | |
| SCHEMBL25215003 | 0.78 | ROCK2 (0.77) | ROCK2ROCK1NCOA1NCOA3ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159469-A1 | NOVEL PHTHALAZINE DERIVATIVE HAVING ECTONUCLOEOTIDE PYROPHOSPHATASE/PHOSPHODIESTE RASE INHIBITORY ACTIVITY, AND USE THEREOF | TXINNO BIOSCIENCE INC. (KR) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159469-A1 | NOVEL PHTHALAZINE DERIVATIVE HAVING ECTONUCLOEOTIDE PYROPHOSPHATASE/PHOSPHODIESTE RASE INHIBITORY ACTIVITY, AND USE THEREOF | ENPP1, ENPP3, PPA1 | ROCK2 2177/4885ROCK1 1268/4885NCOA1 3066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.