SCHEMBL25237641

SCHEMBL25237641

O=C(/C=C/c1ccc(OC(F)(F)F)cc1)c1ccc(O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F3 P13726 3/20 0.68
MAPT P10636 4/20 0.67
RAB9A P51151 3/20 0.67
KMT2A Q03164 3/20 0.67
CYP1B1 Q16678 3/20 0.67
P4HB P07237 2/20 0.67
MEN1 O00255 2/20 0.67
CYP1A1 P04798 2/20 0.67
CALM1 P0DP23 1/20 0.67
ALDH1A1 P00352 1/20 0.67
XDH P47989 1/20 0.67
ABCG2 Q9UNQ0 4/20 0.62
MAOB P27338 4/20 0.62
BCHE P06276 1/20 0.59
MAOA P21397 2/20 0.59
ESR1 P03372 1/20 0.59
ESR2 Q92731 1/20 0.59
CXCL12 P48061 1/20 0.59
POLB P06746 1/20 0.59
CYP3A4 P08684 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25212966 1.00 F3 (0.68) F3MAPTRAB9AKMT2ACYP1B1
SCHEMBL25216348 1.00 F3 (0.68) F3MAPTRAB9AKMT2ACYP1B1
SCHEMBL2647392 0.94 CYP2D6 (0.63) F3MAPTRAB9AKMT2ACYP1B1
SCHEMBL25202905 0.88 XDH (0.67) F3MAPTRAB9AKMT2ACYP1B1
SCHEMBL25196548 0.88 XDH (0.67) F3MAPTRAB9AKMT2ACYP1B1
SCHEMBL28565594 0.88 TNFRSF1A (0.71) F3MAPTRAB9ACYP1B1P4HB
SCHEMBL2665078 0.87 MAOB (0.69) F3MAPTRAB9AKMT2ACYP1B1
SCHEMBL2648722 0.87 MAOB (0.69) F3MAPTRAB9AKMT2ACYP1B1
SCHEMBL2646833 0.87 F3 (0.77) F3MAPTRAB9AKMT2ACYP1B1
SCHEMBL2646835 0.87 F3 (0.77) F3MAPTRAB9AKMT2ACYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B F3 5/4885MAPT 3297/4885RAB9A 480/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 F3 11/4885MAPT 3512/4885RAB9A 1327/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 F3 11/4885MAPT 3512/4885RAB9A 1327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.