Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.69 |
| ▸ | CTSS | P25774 | 2/20 | 0.62 |
| ▸ | CTSL | P07711 | 1/20 | 0.62 |
| ▸ | CTSB | P07858 | 1/20 | 0.62 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.60 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.60 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.60 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.57 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25282460 | 1.00 | CTSK (0.69) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL12829139 | 0.90 | CTSK (0.72) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL25245595 | 0.87 | CTSK (0.74) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL25287997 | 0.87 | CTSK (0.74) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL25286900 | 0.83 | CTSK (0.49) | CTSKCTSSCTSLCTSB | |
| SCHEMBL25248762 | 0.83 | CTSK (0.49) | CTSKCTSSCTSLCTSB | |
| SCHEMBL25284323 | 0.82 | CTSK (0.85) | CTSKCTSSCTSLCTSB | |
| SCHEMBL25282894 | 0.82 | CTSK (0.77) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL25242881 | 0.82 | CTSK (0.85) | CTSKCTSSCTSLCTSB | |
| SCHEMBL21067894 | 0.82 | CTSK (1.00) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12060333-B2 | Aminocarbamoyl compounds for the treatment of viral infections | HOFFMANN-LA ROCHE INC. (US) | 2024-08-13 | — | — | US | disclosed |
| CN-116438160-A | Carbamoyl compounds for the treatment of viral infections | 豪夫迈·罗氏有限公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-4204393-A1 | AMINOCARBAMOYL COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | F. Hoffmann-La Roche AG (CH) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022043374-A1 | AMINOCARBAMOYL COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2022-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12060333-B2 | Aminocarbamoyl compounds for the treatment of viral infections | SARS1, BCAT1, SLC1A5 | CTSK 2290/4885CTSS 1275/4885CTSL 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.