Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IL1B | P01584 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25283763 | 1.00 | ALOX5AP (0.43) | ALOX5APFEN1F2RL3ALDH1A1UCHL1 | |
| SCHEMBL25782074 | 0.89 | ALDH1A1 (0.37) | ALOX5APFEN1ALDH1A1UCHL1USP30 | |
| SCHEMBL25282163 | 0.87 | ALOX5AP (0.40) | ALOX5APFEN1F2RL3ALDH1A1UCHL1 | |
| SCHEMBL25245084 | 0.87 | ALOX5AP (0.40) | ALOX5APFEN1F2RL3ALDH1A1UCHL1 | |
| SCHEMBL31140687 | 0.82 | ALOX5AP (0.40) | ALOX5APFEN1F2RL3ALDH1A1IL1B | |
| SCHEMBL31140673 | 0.80 | P2RX7 (0.43) | ALOX5APFEN1F2RL3ALDH1A1MEN1 | |
| SCHEMBL25245465 | 0.80 | P2RX7 (0.43) | ALOX5APFEN1F2RL3ALDH1A1MEN1 | |
| SCHEMBL25283904 | 0.80 | P2RX7 (0.43) | ALOX5APFEN1F2RL3ALDH1A1MEN1 | |
| SCHEMBL18013360 | 0.79 | SCN9A (0.47) | ALOX5APFEN1ALDH1A1SCN9AAPP | |
| SCHEMBL31615928 | 0.77 | NPC1 (0.47) | ALOX5APFEN1F2RL3ALDH1A1UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118525018-A | Bialkyne compound and application thereof | 上海艾力斯医药科技股份有限公司 | 2024-08-20 | — | — | CN | disclosed |
| WO-2023116779-A1 | DIALKYNE COMPOUND AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2023-06-29 | — | — | WO | disclosed |