Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21093397 | 0.83 | ALDH1A1 (0.43) | CYP2C9CYP2C19HTR2BMAPK14GRIN2B | |
| SCHEMBL7810455 | 0.82 | GRIN2B (0.46) | CYP2C9CYP2C19HTR2BMAPK14FAAH | |
| SCHEMBL21093634 | 0.79 | GRIN2B (0.44) | CYP2C9CYP2C19HTR2BMAPK14GRIN2B | |
| SCHEMBL22234408 | 0.76 | ALDH1A1 (0.46) | — | |
| SCHEMBL21494357 | 0.75 | ALDH1A1 (0.49) | CYP2C9CYP2C19MAPK14GRIN2BMEN1 | |
| SCHEMBL26144434 | 0.74 | AKR1C3 (0.51) | CYP2C9CYP2C19HTR2BMAPK14FAAH | |
| SCHEMBL19612576 | 0.74 | CYP2C9 (0.52) | CYP2C9CYP2C19HTR2BMAPK14FAAH | |
| SCHEMBL3541508 | 0.72 | L3MBTL1 (0.53) | CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL16590793 | 0.71 | GBA1 (0.50) | GRIN2BCCR3GBA1MEN1KMT2A | |
| SCHEMBL26144433 | 0.71 | CYP2C9 (0.43) | CYP2C9CYP2C19HTR2BMAPK14TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110528-A1 | PROCESS FOR THE PREPARATION OF BENZOFURANS | CAMBREX PROFARMACO MILANO S.R.L. (IT) | 2023-06-22 | — | — | WO | disclosed |