Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 2/20 | 0.36 |
| ▸ | CHUK | O15111 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1420429 | 0.79 | AHR (0.47) | AHRCHEK1IMPDH2IMPDH1TNF | |
| SCHEMBL31357932 | 0.79 | AHR (0.47) | AHRCHEK1IMPDH2IMPDH1TNF | |
| SCHEMBL6793252 | 0.78 | IMPDH2 (0.42) | CHEK1IMPDH2IMPDH1RIPK1MCL1 | |
| SCHEMBL19611745 | 0.78 | AHR (0.46) | AHRNR4A2CHEK1IMPDH2IMPDH1 | |
| SCHEMBL18876088 | 0.78 | IMPDH2 (0.42) | CHEK1IMPDH2IMPDH1MAOAMAOB | |
| SCHEMBL21315701 | 0.74 | AHR (0.48) | AHRF7LTA4HF3NR4A2 | |
| SCHEMBL838245 | 0.74 | AHR (0.54) | AHRF7LTA4HF3NR4A2 | |
| SCHEMBL18876051 | 0.74 | IMPDH2 (0.39) | CHEK1IMPDH2IMPDH1MCL1IKBKB | |
| SCHEMBL18876116 | 0.74 | IMPDH2 (0.39) | CHEK1IMPDH2IMPDH1IKBKBCHUK | |
| SCHEMBL18876113 | 0.74 | MCL1 (0.43) | CHEK1IMPDH2IMPDH1MCL1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |