Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5102711 | 0.89 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL6293250 | 0.87 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL19444397 | 0.86 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL23020157 | 0.85 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL13073704 | 0.85 | GRM5 (0.43) | L3MBTL1ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL29031761 | 0.84 | TDP1 (0.49) | L3MBTL1TDP1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28182684 | 0.82 | TDP1 (0.47) | L3MBTL1MEN1KMT2ATDP1HTT | |
| SCHEMBL253769 | 0.82 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL461554 | 0.81 | TDP1 (0.50) | L3MBTL1TDP1KAT2BLIPG | |
| SCHEMBL844538 | 0.81 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | disclosed |