Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23633151 | 0.95 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1CYP3A4LIPGALOX5 | |
| SCHEMBL11198582 | 0.93 | LIPG (0.49) | L3MBTL1ALDH1A1CYP3A4LIPGALOX5 | |
| SCHEMBL5108741 | 0.89 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL6293250 | 0.87 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL252398 | 0.86 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22597437 | 0.85 | GRM5 (0.40) | L3MBTL1ALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29031761 | 0.84 | TDP1 (0.49) | L3MBTL1CYP3A4CYP2D6CYP2C9LIPG | |
| SCHEMBL27939662 | 0.82 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL28182684 | 0.82 | TDP1 (0.47) | L3MBTL1CYP3A4LIPGALOX5PTGS2 | |
| SCHEMBL461554 | 0.81 | TDP1 (0.50) | L3MBTL1LIPGALOX5PTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3228616-B1 | PYRIDINE DERIVATIVES | ASTELLAS PHARMA INC (JP) | 2019-10-16 | — | — | EP | disclosed |
| EP-3228616-A1 | PYRIDINE DERIVATIVES | Astellas Pharma Inc. (JP) | 2017-10-11 | — | — | EP | disclosed |
| CN-1535958-A | Alpha-substituted pyrimidine. thioalkyl and alkyl ether compound | �������Ŷ���Լ��������˾ | 2004-10-13 | — | — | CN | disclosed |
| CN-1152022-C | Alpha-substituted pyrimidine-thioalkyl and alkylether compounds | �������Ŷ���Լ��������˾ | 2004-06-02 | — | — | CN | disclosed |
| CN-1183773-A | Alpha-substituted pyrimidine-thioalkyl and alkylether compounds | UPJOHN CO (US) | 1998-06-03 | — | — | CN | disclosed |