Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25242170 | 0.92 | TYK2 (0.39) | PIK3C3PIK3CATYK2 | |
| SCHEMBL25288932 | 0.90 | TYK2 (0.38) | PIK3C3PIK3CAPIK3CDPIK3CBMTOR | |
| SCHEMBL25283606 | 0.88 | TYK2 (0.34) | PIK3C3PIK3CAPIK3CDPIK3CBMTOR | |
| SCHEMBL25243202 | 0.87 | SLC34A1 (0.35) | PIK3C3TYK2 | |
| SCHEMBL25240241 | 0.86 | TYK2 (0.34) | PIK3C3PIK3CATYK2 | |
| SCHEMBL25286994 | 0.85 | TYK2 (0.31) | PIK3C3TYK2 | |
| SCHEMBL25290634 | 0.85 | TYK2 (0.43) | PIK3C3TYK2 | |
| SCHEMBL25292435 | 0.82 | PIK3C3 (0.34) | PIK3C3PIK3CATYK2 | |
| SCHEMBL25242541 | 0.82 | TYK2 (0.42) | PIK3C3PIK3CATYK2 | |
| SCHEMBL25284264 | 0.82 | MAP4K1 (0.47) | PIK3C3TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | claimed |
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |