Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 7/20 | 0.47 |
| ▸ | TYK2 | P29597 | 8/20 | 0.45 |
| ▸ | ABL1 | P00519 | 4/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25290634 | 0.90 | TYK2 (0.43) | TYK2ABL1PIK3C3 | |
| SCHEMBL25241283 | 0.82 | PIK3C3 (0.34) | TYK2PIK3C3 | |
| SCHEMBL25283606 | 0.80 | TYK2 (0.34) | TYK2PIK3C3 | |
| SCHEMBL25243202 | 0.79 | SLC34A1 (0.35) | TYK2PIK3C3 | |
| SCHEMBL25288932 | 0.78 | TYK2 (0.38) | TYK2PIK3C3 | |
| SCHEMBL25242170 | 0.78 | TYK2 (0.39) | TYK2PIK3C3 | |
| SCHEMBL25282395 | 0.77 | TYK2 (0.53) | MAP4K1TYK2ABL1PIK3C3 | |
| SCHEMBL25240241 | 0.73 | TYK2 (0.34) | TYK2PIK3C3 | |
| SCHEMBL25244564 | 0.72 | CCNT1 (0.42) | MAP4K1TYK2ABL1 | |
| SCHEMBL25286994 | 0.69 | TYK2 (0.31) | TYK2PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | claimed |
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |