Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 11/20 | 0.63 |
| ▸ | CES1 | P23141 | 10/20 | 0.63 |
| ▸ | ELANE | P08246 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281549 | 0.89 | ELANE (0.64) | ELANEALDH1A1PPARG | |
| SCHEMBL22295633 | 0.84 | SRD5A2 (0.61) | ELANEPPARG | |
| SCHEMBL23369312 | 0.84 | SRD5A2 (0.61) | ELANEPPARG | |
| SCHEMBL25250575 | 0.84 | CES2 (0.58) | CES2CES1RAB9ATDP1ALDH1A1 | |
| SCHEMBL322440 | 0.82 | CA1 (0.59) | ALDH1A1TSHRHSD17B10PPARG | |
| SCHEMBL6674207 | 0.81 | TDP1 (0.70) | ELANERAB9ATDP1ALDH1A1TSHR | |
| Benzoic Acid SCHEMBL27552887 | 0.80 | CA1 (0.50) | CES2CES1ELANETDP1ALDH1A1 | |
| SCHEMBL5705949 | 0.80 | MAPT (0.63) | ELANERAB9ATDP1ALDH1A1TSHR | |
| Propanol SCHEMBL28237782 | 0.80 | GAA (0.55) | ELANERAB9AALDH1A1PPARGMAPT | |
| SCHEMBL12338033 | 0.80 | ELANE (0.44) | CES2CES1ELANETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |