Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26379418 | 0.92 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAHTTNPSR1MAPT | |
| SCHEMBL30595569 | 0.92 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAHTTNPSR1MAPT | |
| SCHEMBL26072048 | 0.90 | KDM4C (0.44) | SMN1; SMN2LMNAHTTNPSR1MAPT | |
| SCHEMBL25286311 | 0.86 | LMNA (0.45) | SMN1; SMN2LMNAHTTNPSR1MAPT | |
| SCHEMBL25284067 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHTTNPSR1MAPT | |
| SCHEMBL25293379 | 0.84 | USP2 (0.56) | SMN1; SMN2LMNAHTTNPSR1MAPT | |
| SCHEMBL30486752 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAHTTNPSR1MAPT | |
| SCHEMBL26379378 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAHTTNPSR1MAPT | |
| SCHEMBL26072164 | 0.81 | AURKA (0.46) | SMN1; SMN2TP53KMT2AMEN1ROCK2 | |
| SCHEMBL25242365 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHTTNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12590063-B2 | Phenol derivative | Sumitomo Pharma Co., Ltd. (JP) | 2026-03-31 | — | — | US | disclosed |
| US-20230312474-A1 | PHENOL DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2023-10-05 | — | — | US | disclosed |
| US-20230312474-A1 | PHENOL DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2023-10-05 | — | — | US | disclosed |
| EP-4206184-A1 | PHENOL DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2023-07-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12590063-B2 | Phenol derivative | HDAC3, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HNF4A | SMN1; SMN2 2226/4885LMNA 1741/4885HTT 2192/4885 |
| US-20230312474-A1 | PHENOL DERIVATIVE | TYR, NCOR1, BET1 | SMN1; SMN2 2949/4885LMNA 1203/4885HTT 3055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.