Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.42 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25290995 | 0.89 | NAMPT (0.44) | GPR183KCNH2CNR2EPHX2NAMPT | |
| SCHEMBL25245952 | 0.89 | GPR183 (0.42) | TSHRSMN1; SMN2GPR183KCNH2ALDH1A1 | |
| SCHEMBL1276137 | 0.86 | HPGD (0.60) | TSHRALDH1A1HPGDHTTCHRNB2 | |
| SCHEMBL8318040 | 0.85 | TSHR (0.56) | TSHRSMN1; SMN2ALDH1A1HPGDPOLB | |
| SCHEMBL4696278 | 0.82 | ALDH1A1 (0.68) | TSHRSMN1; SMN2ALDH1A1HPGDCNR2 | |
| SCHEMBL18415359 | 0.82 | HPGD (0.68) | TSHRSMN1; SMN2GPR183KCNH2ALDH1A1 | |
| SCHEMBL28468465 | 0.82 | ALDH1A1 (0.61) | TSHRSMN1; SMN2ALDH1A1HPGDHTT | |
| SCHEMBL25246854 | 0.80 | TSHR (0.39) | TSHRSMN1; SMN2GPR183ALDH1A1HPGD | |
| SCHEMBL1911828 | 0.80 | HPGD (0.72) | TSHRSMN1; SMN2ALDH1A1HPGDPOLB | |
| SCHEMBL25285927 | 0.80 | GPR183 (0.42) | TSHRSMN1; SMN2GPR183KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | claimed |
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |