Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | KHK | P50053 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30454942 | 1.00 | GPR119 (0.40) | GPR119HDAC4GBA1KHKIDH1 | |
| SCHEMBL30954172 | 0.85 | KHK (0.38) | GPR119KHKIDH1IDH2 | |
| SCHEMBL31212741 | 0.85 | KHK (0.38) | GPR119KHKIDH1IDH2 | |
| SCHEMBL25771136 | 0.82 | CXCR2 (0.38) | GPR119HDAC4GBA1KHKIDH1 | |
| SCHEMBL25771310 | 0.82 | GPR119 (0.40) | GPR119 | |
| SCHEMBL31212742 | 0.82 | GPR119 (0.40) | GPR119 | |
| SCHEMBL30455460 | 0.82 | SMN1; SMN2 (0.35) | KHK | |
| SCHEMBL30455751 | 0.80 | KHK (0.37) | KHK | |
| SCHEMBL25250099 | 0.80 | KHK (0.37) | KHK | |
| SCHEMBL21733677 | 0.79 | GPR119 (0.45) | GPR119GBA1CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121378-A1 | (S)-2-(2-METHYLAZETIDIN-1-YL)PYRIMIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 엘지화학 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023121378-A1 | (S)-2-(2-METHYLAZETIDIN-1-YL)PYRIMIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 엘지화학 | 2023-06-29 | — | — | WO | disclosed |