Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25250099 | 0.97 | KHK (0.37) | KHKSMN1; SMN2L3MBTL1GLP1RTRPV1 | |
| SCHEMBL25245827 | 0.88 | KHK (0.35) | KHKSMN1; SMN2L3MBTL1 | |
| SCHEMBL30455460 | 0.86 | SMN1; SMN2 (0.35) | KHKSMN1; SMN2L3MBTL1TRPV1LMNA | |
| SCHEMBL30954183 | 0.83 | KHK (0.40) | KHKSMN1; SMN2L3MBTL1LMNATP53 | |
| SCHEMBL25290738 | 0.83 | KHK (0.40) | KHKSMN1; SMN2L3MBTL1LMNATP53 | |
| SCHEMBL25291965 | 0.82 | KHK (0.46) | KHKLMNATP53 | |
| SCHEMBL30954212 | 0.82 | KHK (0.46) | KHKLMNATP53 | |
| SCHEMBL25244232 | 0.80 | GPR119 (0.40) | KHK | |
| SCHEMBL30454942 | 0.80 | GPR119 (0.40) | KHK | |
| SCHEMBL25253134 | 0.79 | KHK (0.40) | KHKSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121378-A1 | (S)-2-(2-METHYLAZETIDIN-1-YL)PYRIMIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 엘지화학 | 2023-06-29 | — | — | WO | disclosed |