Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 11/20 | 0.45 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 3/20 | 0.42 |
| ▸ | PRKCA | P17252 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31145342 | 1.00 | PIM2 (0.45) | PIM2SHMT2SSTR2KCNH2JAK2 | |
| SCHEMBL31302454 | 0.84 | MEN1 (0.47) | PIM2SHMT2KCNH2ATRDYRK1A | |
| SCHEMBL31145254 | 0.84 | SHMT2 (0.44) | PIM2SHMT2ATRGSK3BDYRK1A | |
| SCHEMBL25292422 | 0.84 | SHMT2 (0.44) | PIM2SHMT2ATRGSK3BDYRK1A | |
| SCHEMBL31302448 | 0.83 | HRH4 (0.42) | PIM2SHMT2KCNH2ATRROCK2 | |
| SCHEMBL31302363 | 0.81 | CYP3A4 (0.43) | PIM2SHMT2KCNH2ATRROCK2 | |
| SCHEMBL25293080 | 0.81 | PIM1 (0.44) | PIM2SHMT2ATRPRKCAPRKCQ | |
| SCHEMBL31145325 | 0.81 | PIM1 (0.44) | PIM2SHMT2ATRPRKCAPRKCQ | |
| SCHEMBL25293017 | 0.80 | SHMT2 (0.42) | PIM2SHMT2PIM1PIM3 | |
| SCHEMBL25287892 | 0.80 | PIM2 (0.42) | PIM2SHMT2ROCK2ROCK1CDC42BPB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250101436-A1 | APTAMERS AND SMALL MOLECULE LIGANDS | MeiraGTx Gene Regulation Limited (GB) | 2025-03-27 | — | — | US | disclosed |
| EP-4448769-A2 | APTAMERS AND SMALL MOLECULE LIGANDS | Meiragtx UK II Limited (GB) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023111686-A2 | APTAMERS AND SMALL MOLECULE LIGANDS | MEIRAGTX UK II LIMITED (GB) | 2023-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250101436-A1 | APTAMERS AND SMALL MOLECULE LIGANDS | RNGTT, SLIRP, SNRPE | PIM2 2313/4885SHMT2 964/4885SSTR2 2933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.