Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.76 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.76 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CTSS | P25774 | 4/20 | 0.59 |
| ▸ | CTSL | P07711 | 3/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | PYGL | P06737 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CCKBR | P32239 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25517392 | 0.89 | TAS1R3 (0.78) | TAS1R3TAS1R1GAALMNACTSS | |
| SCHEMBL20853657 | 0.89 | TAS1R3 (0.78) | TAS1R3TAS1R1GAALMNACTSS | |
| SCHEMBL25197064 | 0.89 | TAS1R3 (0.78) | TAS1R3TAS1R1GAALMNACTSS | |
| SCHEMBL30174792 | 0.86 | TAS1R3 (1.00) | TAS1R3TAS1R1GAALMNACTSS | |
| SCHEMBL25517395 | 0.86 | TAS1R3 (1.00) | TAS1R3TAS1R1GAALMNACTSS | |
| SCHEMBL702414 | 0.86 | TAS1R3 (1.00) | TAS1R3TAS1R1GAALMNACTSS | |
| SCHEMBL702413 | 0.86 | TAS1R3 (1.00) | TAS1R3TAS1R1GAALMNACTSS | |
| SCHEMBL25286173 | 0.85 | TAS1R3 (0.73) | TAS1R3TAS1R1GAALMNACTSS | |
| SCHEMBL25244468 | 0.85 | TAS1R3 (0.73) | TAS1R3TAS1R1GAALMNACTSS | |
| SCHEMBL25244832 | 0.83 | TAS1R3 (0.70) | TAS1R3TAS1R1GAALMNACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067894-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1067894-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-01-17 | — | — | EP | claimed |
| WO-1999059526-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-25 | — | — | WO | claimed |