Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1097551 | 0.92 | SGMS2 (0.54) | MEN1KMT2ASGMS2BRD4MAPT | |
| SCHEMBL9724299 | 0.84 | HPGD (0.56) | SGMS2BRD4MAPTL3MBTL1CYP2C9 | |
| SCHEMBL5120937 | 0.83 | CA12 (0.59) | SGMS2BRD4MAPTL3MBTL1TDP1 | |
| SCHEMBL978857 | 0.82 | HTT (0.64) | MEN1KMT2ASGMS2BRD4MAPT | |
| SCHEMBL4947232 | 0.82 | MAOB (0.61) | BRD4MAPTL3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL71081 | 0.82 | SGMS2 (0.67) | MEN1KMT2ASGMS2BRD4MAPT | |
| SCHEMBL30468871 | 0.82 | SGMS2 (0.67) | MEN1KMT2ASGMS2BRD4MAPT | |
| SCHEMBL13044291 | 0.81 | SGMS2 (0.55) | MEN1KMT2ASGMS2MAPTL3MBTL1 | |
| SCHEMBL2255018 | 0.81 | MAPT (0.51) | KMT2AMAPTL3MBTL1SMN1; SMN2GAA | |
| SCHEMBL29790826 | 0.81 | MAPT (0.51) | KMT2AMAPTL3MBTL1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4455139-A1 | COMPOUND AS FAK INHIBITOR AND USE THEREOF | Wigen Biomedicine Technology (Shanghai) Co., Ltd. (CN) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023116527-A1 | COMPOUND AS FAK INHIBITOR AND USE THEREOF | 微境生物医药科技(上海)有限公司 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023116527-A1 | COMPOUND AS FAK INHIBITOR AND USE THEREOF | 微境生物医药科技(上海)有限公司 | 2023-06-29 | — | — | WO | disclosed |