SCHEMBL978857

SCHEMBL978857

COC(=O)c1ccccc1OCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.64
SGMS2 Q8NHU3 3/20 0.63
NPC1 O15118 1/20 0.60
GAA P10253 1/20 0.58
PTGER1 P34995 1/20 0.57
SLC6A3 Q01959 1/20 0.57
BRD4 O60885 1/20 0.56
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
LMNA P02545 1/20 0.56
MAPT P10636 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
ALDH1A1 P00352 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10411181 0.95 SLC6A3 (0.58) HTTSGMS2SLC6A3KMT2ALMNA
SCHEMBL4002825 0.90 FFAR4 (0.55) HTTSGMS2NPC1SLC6A3LMNA
SCHEMBL5309541 0.89 KMT2A (0.64) NPC1SLC6A3MEN1KMT2ALMNA
SCHEMBL13044291 0.89 SGMS2 (0.55) HTTSGMS2GAASLC6A3MEN1
SCHEMBL1097551 0.88 SGMS2 (0.54) HTTSGMS2NPC1GAAPTGER1
SCHEMBL29930977 0.88 SGMS2 (0.54) HTTSGMS2NPC1GAAPTGER1
SCHEMBL25720776 0.88 MAPT (0.63) HTTSGMS2NPC1GAAPTGER1
SCHEMBL1346892 0.88 ALDH1A1 (0.56) HTTSGMS2KMT2ALMNAMAPT
SCHEMBL1305662 0.88 HPGD (0.57) HTTSGMS2NPC1GAAPTGER1
SCHEMBL5940976 0.88 SGMS2 (0.54) HTTSGMS2NPC1GAAPTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3678203-B1 METHOD FOR PREPARING ORGANIC ELECTRONIC DEVICE LG CHEMICAL LTD (KR) 2025-06-18 EP disclosed
US-20250186433-A1 ACSS2 INHIBITORS AND METHODS OF USE THEREOF EPIVARIO, INC. 2025-06-12 US disclosed
US-12202997-B2 Encapsulating composition LG CHEM, LTD. (KR) 2025-01-21 US disclosed
EP-3683854-B1 METHOD FOR ENCAPSULATING ORGANIC ELECTRONIC ELEMENT LG CHEMICAL LTD (KR) 2024-11-27 EP disclosed
US-12133852-B2 ACSS2 inhibitors and methods of use thereof EPIVARIO, INC. (US) 2024-11-05 US disclosed
US-12104075-B2 Encapsulating composition LG CHEM, LTD. (KR) 2024-10-01 US disclosed
US-12097629-B2 Razor cartridge BIC Violex Single Member S.A. (GR) 2024-09-24 US disclosed
US-12096648-B2 Method for encapsulating organic electronic element LG CHEM, LTD. (KR) 2024-09-17 US disclosed
EP-3800228-B1 SEALANT COMPOSITION LG CHEMICAL LTD (KR) 2024-07-31 EP disclosed
US-12030988-B2 Encapsulating composition LG CHEM, LTD. (KR) 2024-07-09 US disclosed
US-4267187-A AS PHARMACEUTICALS IN TREATING CARDIOVASCULAR DISSORDERS BASF AKTIENGESELLSCHAFT (DE) 1981-05-12 US disclosed
US-4240964-A PHARMACOLOGICAL CHEMICAL INTERMEDIATE FORM BY CYCLIZING REACTION PRODUCT OF O-BENZYLOXYBENZOIC ACID ALLYLAMIDE AND PHOSGENE BASF AKTIENGESELLSCHAFT (DE) 1980-12-23 US disclosed
US-4148900-A ANTIALLERGIC CARLO ERBA S.P.A. (IT) 1979-04-10 US disclosed
US-4115567-A TREATMENT OF ALLERGIES CARLO ERBA S. P. A. (IT) 1978-09-19 US disclosed
US-4104274-A 1-Substituted-2-(2-pyridinyl)ethanone N-oxides WARNER-LAMBERT COMPANY (US) 1978-08-01 US disclosed
US-4083953-A ANTIALLERGENS CARLO ERBA, S.P.A. (IT) 1978-04-11 US disclosed
US-4076720-A 1-Substituted-2-(2-pyridinyl)ethanone N-oxides WARNER-LAMBERT COMPANY (US) 1978-02-28 US disclosed
US-4065467-A ANTIALLERGENS, ANTIULCER AGENTS, TREATMENT OF RESPIRATORY SYSTEM AND PULMONARY DISORDERS CARLO ERBA, S. P. A. (IT) 1977-12-27 US disclosed
US-4056619-A 1-Substituted-2-(2-pyridinyl)ethanone N-oxides WARNER-LAMBERT COMPANY (US) 1977-11-01 US disclosed
US-3998974-A Comestibles containing non-nutritive flavoring DYNAPOL CORPORATION (US) 1976-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250186433-A1 ACSS2 INHIBITORS AND METHODS OF USE THEREOF ACSS2, GLS2, ADSS2 HTT 4784/4885SGMS2 73/4885NPC1 2991/4885
US-12133852-B2 ACSS2 inhibitors and methods of use thereof ACSS2, GLS2, ADSS2 HTT 4784/4885SGMS2 73/4885NPC1 2991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.