Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1073150 | 1.00 | LMNA (0.44) | LMNACYP1A2CYP2C19TSHRTDP1 | |
| SCHEMBL1073148 | 1.00 | LMNA (0.44) | LMNACYP1A2CYP2C19TSHRTDP1 | |
| SCHEMBL294875 | 0.85 | LMNA (0.60) | LMNACYP1A2CYP2C19TSHRTDP1 | |
| SCHEMBL12212691 | 0.83 | LMNA (0.41) | LMNACYP1A2CYP2C19TSHRTDP1 | |
| SCHEMBL2520167 | 0.83 | LMNA (0.41) | LMNACYP1A2CYP2C19TSHRTDP1 | |
| SCHEMBL2167686 | 0.81 | LMNA (0.47) | LMNACYP1A2CYP2C19TSHRTDP1 | |
| SCHEMBL2167679 | 0.81 | LMNA (0.47) | LMNACYP1A2CYP2C19TSHRTDP1 | |
| SCHEMBL1073000 | 0.81 | LMNA (0.47) | LMNACYP1A2CYP2C19TSHRTDP1 | |
| SCHEMBL11239722 | 0.81 | LMNA (0.47) | LMNACYP1A2CYP2C19TSHRTDP1 | |
| SCHEMBL2167676 | 0.81 | LMNA (0.47) | LMNACYP1A2CYP2C19TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039499-B2 | Ester compound and its use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-10-18 | — | — | US | disclosed |