SCHEMBL2167679

SCHEMBL2167679

COC(=O)C1C(/C=C(/C)C=O)C1(C)C

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
TSHR P16473 3/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2C19 P33261 2/20 0.37
TDP1 Q9NUW8 3/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
TRPV1 Q8NER1 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
ADRA2A P08913 1/20 0.30
CNR1 P21554 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11239722 1.00 LMNA (0.47) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL1073000 1.00 LMNA (0.47) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL1072998 1.00 LMNA (0.47) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL2167686 1.00 LMNA (0.47) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL2167676 1.00 LMNA (0.47) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL2219671 0.83 LMNA (0.66) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL6439369 0.83 LMNA (0.66) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL3683341 0.83 LMNA (0.66) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL10989214 0.83 LMNA (0.66) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL294747 0.83 LMNA (0.66) LMNATSHRCYP1A2CYP2C19TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2540701-B1 PROCESS FOR PRODUCTION OF CYCLOPROPANECARBOXYLIC ACID ESTER COMPOUND SUMITOMO CHEMICAL CO (JP) 2014-10-22 EP disclosed
EP-2540701-A1 PROCESS FOR PRODUCTION OF CYCLOPROPANECARBOXYLIC ACID ESTER COMPOUND Sumitomo Chemical Co., Ltd (JP) 2013-01-02 EP disclosed
EP-2537828-A1 METHOD FOR PRODUCING CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID SALT Sumitomo Chemical Company, Limited (JP) 2012-12-26 EP disclosed
US-20120323034-A1 PROCESS FOR PRODUCTION OF CYCLOPROPANECARBOXYLIC ACID ESTER COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-12-20 US disclosed
US-20120310003-A1 METHOD FOR PRODUCING CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID SALT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-12-06 US disclosed
EP-1970368-B1 METHOD FOR PRODUCING OLEFIN COMPOUND SUMITOMO CHEMICAL CO (JP) 2012-08-29 EP disclosed
US-7985872-B2 Method for producing olefin compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-26 US disclosed
US-7700799-B2 Method for producing (2-formyl-1-alkenyl) cyclopropane compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-20 US disclosed
US-20090137839-A1 METHOD FOR PRODUCING (2-FORMYL-1-ALKENYL) CYCLOPROPANE COMPOUND SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2009-05-28 US disclosed
US-7498459-B2 Method for producing (1-alkenyl)cyclopropane compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-03 US disclosed
US-20090036620-A1 METHOD FOR PRODUCING OLEFIN COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-05 US disclosed
EP-1970368-A1 METHOD FOR PRODUCING OLEFIN COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-09-17 EP disclosed
US-20070197818-A1 Method for producing (1-alkenyl) cyclopropane compound SUMITOMO CHEMICAL COMPANY, LIMITED 2007-08-23 US disclosed
EP-1728781-A1 PROCESS FOR PRODUCTION OF (1-ALKENYL)CYCLOPROPANES Sumitomo Chemical Company, Limited (JP) 2006-12-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137839-A1 METHOD FOR PRODUCING (2-FORMYL-1-ALKENYL) CYCLOPROPANE COMPOUND ACSL3, ACSL1, ARL1 LMNA 2696/4885TSHR 3074/4885CYP1A2 53/4885
US-20120310003-A1 METHOD FOR PRODUCING CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID SALT MCCC2, AOC2, DDC LMNA 2375/4885TSHR 1331/4885CYP1A2 287/4885
US-20120323034-A1 PROCESS FOR PRODUCTION OF CYCLOPROPANECARBOXYLIC ACID ESTER COMPOUND CYP2E1, POR, CYP2F1 LMNA 3832/4885TSHR 716/4885CYP1A2 10/4885
US-20070197818-A1 Method for producing (1-alkenyl) cyclopropane compound ACSL3, ARL1, ACSL1 LMNA 3763/4885TSHR 3751/4885CYP1A2 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.