Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 6/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | TET3 | O43151 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25239224 | 0.85 | PARP1 (0.37) | TSHRPOLBMAPTEGLN2SMN1; SMN2 | |
| SCHEMBL25237230 | 0.81 | KDM4E (0.40) | KDM4CTSHRKDM4EALDH1A1POLB | |
| SCHEMBL31309309 | 0.72 | TPMT (0.39) | TTRKDM5AKDM4CKDM5BALOX15 | |
| SCHEMBL31114292 | 0.70 | KDM5A (0.33) | KDM5AKDM4CKDM5BPIK3CA | |
| SCHEMBL15243426 | 0.69 | HCAR2 (0.41) | KDM5AKDM4CKDM5BNAPRTKDM4E | |
| SCHEMBL31114289 | 0.68 | PTGER4 (0.41) | KDM5AKDM4CKDM5BMAPTPIK3CA | |
| SCHEMBL15232225 | 0.68 | HCAR2 (0.40) | KDM5AKDM4CKDM5BNAPRTKDM4E | |
| SCHEMBL3081703 | 0.68 | ESR1 (0.47) | KDM5AKDM4CKDM5BNAPRTKDM4E | |
| SCHEMBL31309518 | 0.67 | ALDH1A1 (0.34) | TTRKDM4CALDH1A1POLBKDM4A | |
| SCHEMBL2715907 | 0.63 | DRD2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116779-A1 | DIALKYNE COMPOUND AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023116779-A1 | DIALKYNE COMPOUND AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2023-06-29 | — | — | WO | disclosed |