Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29809179 | 1.00 | MAPT (0.44) | MAPTGAANPSR1KMT2AHTT | |
| SCHEMBL25295791 | 0.85 | MAPT (0.44) | MAPTGAANPSR1KMT2AHTT | |
| SCHEMBL31123059 | 0.85 | ALDH1A1 (0.48) | MAPTGAANPSR1KMT2AHTT | |
| SCHEMBL25252935 | 0.85 | KMT2A (0.39) | MAPTGAANPSR1KMT2AHTT | |
| SCHEMBL25298464 | 0.79 | ALDH1A1 (0.51) | NPSR1KMT2AHTTLMNAALDH1A1 | |
| SCHEMBL12225198 | 0.79 | ALDH1A1 (0.48) | MAPTGAANPSR1KMT2AHTT | |
| SCHEMBL29809012 | 0.79 | ALDH1A1 (0.51) | NPSR1KMT2AHTTLMNAALDH1A1 | |
| SCHEMBL30088515 | 0.78 | MAPT (0.43) | MAPTGAANPSR1KMT2AHTT | |
| SCHEMBL11641252 | 0.77 | MAPT (0.45) | MAPTGAANPSR1HTTKDM4E | |
| SCHEMBL31123052 | 0.75 | MAPT (0.66) | MAPTNPSR1KMT2AHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051287-A1 | METHOD FOR PREPARATION OF BENZIMIDAZOLE DERIVATIVES | HK INNO.N CORPORATION (KR) | 2025-02-13 | — | — | US | disclosed |
| CN-116354889-B | Process for preparing benzimidazole derivatives | 怡诺安有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-119100992-A | Preparation method of tergolian intermediate and derivative thereof | 帕潘纳(北京)科技有限公司 | 2024-12-10 | — | — | CN | disclosed |
| EP-4457216-A1 | METHOD FOR PREPARATION OF BENZIMIDAZOLE DERIVATIVES | HK inno.N Corporation (KR) | 2024-11-06 | — | — | EP | disclosed |
| WO-2023128525-A1 | METHOD FOR PREPARATION OF BENZIMIDAZOLE DERIVATIVES | HK INNO.N CORPORATION (KR) | 2023-07-06 | — | — | WO | disclosed |
| CN-116354889-A | Process for preparing benzimidazole derivatives | 怡诺安有限公司 | 2023-06-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051287-A1 | METHOD FOR PREPARATION OF BENZIMIDAZOLE DERIVATIVES | CYP3A4, CYP3A5, TMBIM6 | MAPT 3499/4885GAA 404/4885NPSR1 4581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.