Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 4/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22092272 | 0.81 | MEN1 (0.40) | NOTUMMEN1KMT2AL3MBTL1CACNA1G | |
| SCHEMBL21503622 | 0.81 | SMN1; SMN2 (0.43) | NOTUMMEN1KMT2AL3MBTL1IDO1 | |
| SCHEMBL11502287 | 0.79 | RAB9A (0.50) | MEN1KMT2AL3MBTL1IDO1NPC1 | |
| SCHEMBL25301900 | 0.79 | FFAR4 (0.39) | NOTUMMEN1KMT2AL3MBTL1CACNA1G | |
| SCHEMBL25260476 | 0.78 | NOTUM (0.35) | NOTUMMEN1KMT2AL3MBTL1CACNA1G | |
| SCHEMBL23062630 | 0.77 | NOTUM (0.40) | NOTUMMEN1KMT2AL3MBTL1CACNA1G | |
| SCHEMBL22719359 | 0.77 | NOTUM (0.40) | NOTUMMEN1KMT2AL3MBTL1CACNA1G | |
| SCHEMBL1727867 | 0.77 | MEN1 (0.41) | NOTUMMEN1KMT2AL3MBTL1CACNA1G | |
| SCHEMBL16843295 | 0.77 | NOTUM (0.40) | NOTUMMEN1KMT2AL3MBTL1CACNA1G | |
| SCHEMBL12151773 | 0.77 | PDE10A (0.43) | NOTUMMEN1KMT2AL3MBTL1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125681-A1 | HETEROCYCLIC COMPOUNDS | BEIGENE, LTD. (KY) | 2023-07-06 | — | — | WO | disclosed |