SCHEMBL25250563

SCHEMBL25250563

COc1ccc2[nH]nc(CCN(C)C)c2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 5/20 0.60
▸ HTR2C P28335 4/20 0.60
▸ HTR2B P41595 3/20 0.60
▸ HTR6 P50406 9/20 0.57
▸ HTR1A P08908 4/20 0.57
▸ HTR1D P28221 4/20 0.57
▸ HTR7 P34969 4/20 0.57
▸ HTR5A P47898 4/20 0.57
▸ HTR1E P28566 3/20 0.57
▸ HTR3E A5X5Y0 1/20 0.57
▸ HTR3B O95264 1/20 0.57
▸ CYP1A2 P05177 1/20 0.57
▸ CYP2D6 P10635 1/20 0.57
▸ CYP2C9 P11712 1/20 0.57
▸ HTR1B P28222 1/20 0.57
▸ HTR1F P30939 1/20 0.57
▸ HTR3A P46098 1/20 0.57
▸ MTNR1A P48039 1/20 0.57
▸ MTNR1B P49286 1/20 0.57
▸ HTR4 Q13639 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL25257248 0.99 HTR2A (0.59) HTR2AHTR2CHTR2BHTR6HTR1A
SCHEMBL25249896 0.88 HTR2A (0.51) HTR2AHTR2CHTR2BHTR6HTR1A
SCHEMBL30566021 0.88 HTR2A (0.51) HTR2AHTR2CHTR2BHTR6HTR1A
SCHEMBL25249523 0.87 HTR2A (0.46) HTR2AHTR2CHTR2BHTR6HTR1A
SCHEMBL30565954 0.86 HTR1A (0.59) HTR2AHTR2CHTR2BHTR6HTR1A
SCHEMBL25259753 0.86 HTR1A (0.59) HTR2AHTR2CHTR2BHTR6HTR1A
Hydrochloric Acid SCHEMBL30565940 0.85 HTR2A (0.45) HTR2AHTR2CHTR2BHTR6HTR1A
SCHEMBL25288157 0.85 HTR1A (0.48) HTR2AHTR2CHTR2BHTR6HTR1A
Hydrochloric Acid SCHEMBL25249135 0.85 HTR1A (0.57) HTR2AHTR2CHTR2BHTR6HTR1A
SCHEMBL30565956 0.85 HTR1A (0.48) HTR2AHTR2CHTR2BHTR6HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 — — EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 — — US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 — — US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 — — US disclosed
US-20250163044-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-05-22 — — US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 — — WO disclosed
CN-118974044-A Compounds of formula (I) 赛洛私人有限公司 2024-11-15 — — CN disclosed
EP-4452979-A1 COMPOUNDS Psylo Pty Ltd (AU) 2024-10-30 — — EP disclosed
WO-2023115165-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-06-29 — — WO disclosed
WO-2023115165-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-06-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB HTR2A 94/4885HTR2C 23/4885HTR2B 114/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB HTR2A 94/4885HTR2C 23/4885HTR2B 114/4885
US-20250163044-A1 COMPOUNDS NLN, SLC18A2, PYGB HTR2A 94/4885HTR2C 23/4885HTR2B 114/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB HTR2A 94/4885HTR2C 23/4885HTR2B 114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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