Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | GLI1 | P08151 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365854 | 0.81 | P2RX7 (0.40) | P2RX7ACE | |
| SCHEMBL8232195 | 0.81 | P2RX7 (0.40) | P2RX7BRD4 | |
| SCHEMBL288353 | 0.81 | P2RX7 (0.40) | P2RX7ACE | |
| SCHEMBL5081569 | 0.81 | P2RX7 (0.40) | P2RX7ACE | |
| SCHEMBL6999553 | 0.81 | P2RX7 (0.40) | P2RX7ACE | |
| Hydrochloric Acid SCHEMBL28572830 | 0.79 | P2RX7 (0.39) | P2RX7ACE | |
| Lithium Ion SCHEMBL30619228 | 0.78 | P2RX7 (0.38) | P2RX7BRD4 | |
| SCHEMBL31391836 | 0.76 | P2RX7 (0.46) | P2RX7BRD4SORT1 | |
| SCHEMBL8231477 | 0.76 | P2RX7 (0.40) | P2RX7BRD4ACE | |
| SCHEMBL8422246 | 0.76 | P2RX7 (0.40) | P2RX7BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125918-A1 | DNA POLYMERASE THETA INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-07-06 | — | — | WO | disclosed |