Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 2/20 | 0.38 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30487414 | 1.00 | NAMPT (0.45) | NAMPTESR2BRD3NR1H2HDAC1 | |
| SCHEMBL30487378 | 0.88 | ESR2 (0.44) | NAMPTESR2BRD3NR1H2HDAC1 | |
| SCHEMBL25290544 | 0.88 | ESR2 (0.44) | NAMPTESR2BRD3NR1H2HDAC1 | |
| SCHEMBL25251450 | 0.79 | ESR2 (0.44) | NAMPTESR2BRD3NR1H2HDAC1 | |
| SCHEMBL30487370 | 0.79 | ESR2 (0.44) | NAMPTESR2BRD3NR1H2HDAC1 | |
| SCHEMBL13337056 | 0.74 | DPP9 (0.58) | NAMPTESR2NR1H2HDAC1DPP8 | |
| SCHEMBL19981606 | 0.70 | NR1H2 (0.72) | ESR2NR1H2HDAC1DPP8DPP9 | |
| SCHEMBL31067462 | 0.70 | ESR2 (0.74) | NAMPTESR2NR1H2HDAC1DPP8 | |
| SCHEMBL25305715 | 0.69 | HDAC1 (0.45) | ESR2BRD3HDAC1HDAC2GPR119 | |
| SCHEMBL17369316 | 0.69 | ESR2 (0.48) | NAMPTESR2NR1H2HDAC1DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125935-A1 | BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |