Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25292326 | 1.00 | KCNH2 (0.43) | KCNH2CYP2C9CYP2C8CYP1A2HPSE | |
| SCHEMBL21988910 | 0.93 | KCNH2 (0.42) | KCNH2CYP2C9CYP2C8CYP1A2ALDH1A1 | |
| SCHEMBL21988912 | 0.93 | KCNH2 (0.42) | KCNH2CYP2C9CYP2C8CYP1A2ALDH1A1 | |
| SCHEMBL21988999 | 0.91 | KCNH2 (0.45) | KCNH2CYP2C9CYP2C8CYP1A2 | |
| SCHEMBL21989001 | 0.91 | KCNH2 (0.45) | KCNH2CYP2C9CYP2C8CYP1A2 | |
| SCHEMBL22045568 | 0.80 | KCNH2 (0.34) | KCNH2HPSEALDH1A1HSD17B10 | |
| SCHEMBL21988938 | 0.78 | KCNH2 (0.44) | KCNH2CYP2C9CYP2C8CYP1A2ALDH1A1 | |
| SCHEMBL21988939 | 0.78 | KCNH2 (0.44) | KCNH2CYP2C9CYP2C8CYP1A2ALDH1A1 | |
| SCHEMBL25301370 | 0.78 | KCNH2 (0.49) | KCNH2CYP2C9CYP2C8CYP1A2HPSE | |
| SCHEMBL25301369 | 0.78 | KCNH2 (0.49) | KCNH2CYP2C9CYP2C8CYP1A2HPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382892-A1 | Chemical Compounds | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-11702405-B2 | Chemical compounds | PFIZER INC. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702405-B2 | Chemical compounds | HBZ, HBB, HBS1L | KCNH2 1300/4885CYP2C9 66/4885CYP2C8 284/4885 |
| US-20230382892-A1 | Chemical Compounds | HBZ, HBB, HBS1L | KCNH2 1300/4885CYP2C9 66/4885CYP2C8 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.