Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | TTR | P02766 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | RECQL | P46063 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | FTO | Q9C0B1 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 1.00 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 1.00 |
| ▸ | CASP7 | P55210 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rhein SCHEMBL29404324 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| Rhein SCHEMBL8012677 | 0.98 | ALDH1A1 (0.97) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| Rhein SCHEMBL23632868 | 0.98 | ALDH1A1 (0.97) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| Rhein SCHEMBL1357918 | 0.98 | ALDH1A1 (0.97) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| Rhein SCHEMBL23632879 | 0.98 | ALDH1A1 (0.97) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| Rhein SCHEMBL23633120 | 0.98 | ALDH1A1 (0.97) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| Rhein SCHEMBL23632984 | 0.98 | ALDH1A1 (0.97) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| Rhein SCHEMBL1356821 | 0.98 | ALDH1A1 (0.97) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| Rhein SCHEMBL526035 | 0.98 | ALDH1A1 (0.97) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| Rhein SCHEMBL8618738 | 0.98 | ALDH1A1 (0.97) | ALDH1A1MAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 15854 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615506-A1 | USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES | Sahin, Fikret (TR) | 2025-09-17 | — | — | EP | claimed |
| CN-120072095-A | Network pharmacology and molecular docking prediction method of traditional Chinese medicine composition | 天津现代创新中药科技有限公司 | 2025-05-30 | — | — | CN | claimed |
| EP-4187242-B1 | QUALITY CONTROL METHOD OF DAMPNESS-RESOLVING AND TOXIN-VANQUISHING COMPOSITION | Guangdong yifang pharmaceutical co ltd (CN) | 2025-01-01 | — | — | EP | claimed |
| WO-2024258363-A1 | USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES | SAHIN FIKRET (TR) | 2024-12-19 | — | — | WO | claimed |
| CN-118320073-A | Vaccine composition and preparation method and application thereof | 国家纳米科学中心 | 2024-07-12 | — | — | CN | claimed |
| CN-118325217-A | High-flame-retardance composite material for battery-changing cabinet and preparation method thereof | 广东众森实业发展有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-118320074-A | CGAS-STING hydrogel agonist and preparation method and application thereof | 国家纳米科学中心 | 2024-07-12 | — | — | CN | claimed |
| WO-2024147142-A1 | PLANT EXTRACTS WITH HERBICIDAL ACTIVITY | AGREMATCH LTD. (IL) | 2024-07-11 | — | — | WO | claimed |
| CN-118304466-A | PVA/sodium carboxymethylcellulose oxide double-network hydrogel wound dressing and preparation method and application thereof | 烟台大学 | 2024-07-09 | — | — | CN | claimed |
| CN-118286150-A | Rhein-loaded double-dynamic cross-linked polysaccharide-based hydrogel and preparation method thereof | 烟台大学 | 2024-07-05 | — | — | CN | claimed |
| EP-0498707-A1 | Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent | L'OREAL (FR) | 1992-08-12 | — | — | EP | claimed |
| EP-0264989-B1 | GALENIC FORMULATIONS FOR ORAL USE OF RHEIN DERIVATIVES WITH DELAYED RELEASE FOR THERAPEUTICAL USE | PROTER S.p.A. (IT) | 1991-12-18 | — | — | EP | claimed |
| WO-1991015954-A1 | ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-31 | — | — | WO | claimed |
| US-4861599-A | Galenic formulations for oral use of rhein derivatives with delayed release for therapeutical use | PROTER S.P.A. (IT) | 1989-08-29 | — | — | US | claimed |
| EP-0264989-A1 | Galenic formulations for oral use of rhein derivatives with delayed release for therapeutical use | PROTER S.p.A. (IT) | 1988-04-27 | — | — | EP | claimed |
| EP-0251345-A2 | Method for manufacturing manure materials, apparatus for applying this method, and manure materials obtained with the application of this method | Bergsma, Jantinus (NL) | 1988-01-07 | — | — | EP | claimed |
| US-4715736-A | Process for determining optimum keyboard formats for a given language | FWM ENTERPRISES, INC. (US) | 1987-12-29 | — | — | US | claimed |
| US-4602913-A | Use of hydroxyanthraquinones for the coloration of human keratin fibres | L'OREAL (FR) | 1986-07-29 | — | — | US | claimed |
| US-4466828-A | Process for smelting nickel | TOYO ENGINEERING CORPORATION (JP) | 1984-08-21 | — | — | US | claimed |
| US-4244968-A | HYDROXY- AND AMINO-ANTHRAQUINONES | PROTER S.P.A. (IT) | 1981-01-13 | — | — | US | claimed |