Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25721164 | 0.81 | HDAC1 (0.48) | HDAC1HDAC6HDAC3NCOR2 | |
| SCHEMBL30448505 | 0.81 | HDAC1 (0.48) | HDAC1HDAC6HDAC3NCOR2 | |
| SCHEMBL13575595 | 0.81 | HPGD (0.56) | HDAC1HDAC6HDAC3L3MBTL1 | |
| SCHEMBL767860 | 0.79 | HDAC1 (0.48) | HDAC1HDAC6HDAC3NCOR2HDAC2 | |
| SCHEMBL15631040 | 0.79 | HDAC1 (0.63) | HDAC1HDAC6HDAC3MAPK1 | |
| SCHEMBL15630979 | 0.79 | HDAC1 (0.63) | HDAC1HDAC6HDAC3MAPK1 | |
| SCHEMBL15610485 | 0.79 | HDAC1 (0.63) | HDAC1HDAC6HDAC3MAPK1 | |
| SCHEMBL25232222 | 0.79 | ALDH1A1 (0.52) | HDAC1HDAC6HDAC3L3MBTL1HDAC2 | |
| SCHEMBL29582367 | 0.79 | NPC1 (0.65) | HDAC1HDAC6HDAC3MAPK1L3MBTL1 | |
| SCHEMBL25212149 | 0.78 | HDAC3 (0.46) | HDAC1HDAC6HDAC3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091565-A1 | NSD2-TARGETED CHEMICAL DEGRADERS AND COMPOSITIONS AND METHODS OF USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-05-25 | — | — | WO | disclosed |