Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP4 | P49662 | 1/20 | 0.37 |
| ▸ | CASP5 | P51878 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30245369 | 1.00 | QPCT (0.41) | QPCTMAPTNPC1AGXTKDM4E | |
| SCHEMBL29194739 | 0.94 | QPCT (0.39) | QPCTMAPTNPC1AGXTKDM4E | |
| SCHEMBL30245577 | 0.94 | AGXT (0.44) | QPCTMAPTNPC1AGXTKDM4E | |
| SCHEMBL30245239 | 0.94 | QPCT (0.41) | QPCTMAPTNPC1KDM4EF10 | |
| SCHEMBL25253113 | 0.94 | QPCT (0.41) | QPCTMAPTNPC1KDM4EF10 | |
| SCHEMBL30245601 | 0.92 | AGXT (0.43) | QPCTMAPTNPC1AGXTKDM4E | |
| SCHEMBL25260059 | 0.91 | QPCT (0.37) | QPCTMAPTNPC1AGXTKDM4E | |
| SCHEMBL30245826 | 0.91 | QPCT (0.37) | QPCTMAPTNPC1AGXTKDM4E | |
| SCHEMBL25290109 | 0.89 | ALDH1A1 (0.42) | MAPTNPC1ALDH1A1TSHRHRH3 | |
| SCHEMBL30245104 | 0.89 | ALDH1A1 (0.42) | MAPTNPC1ALDH1A1TSHRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | claimed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |