Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.37 |
| ▸ | CETP | P11597 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP4 | P49662 | 1/20 | 0.36 |
| ▸ | CASP5 | P51878 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30245239 | 1.00 | QPCT (0.41) | QPCTF10CNR1CNR2LTA4H | |
| SCHEMBL29194527 | 0.94 | ABCB1 (0.39) | QPCTF10CNR1CNR2LTA4H | |
| SCHEMBL30245554 | 0.94 | VNN1 (0.43) | QPCTF10ABCB1CETPKDM4E | |
| SCHEMBL30245369 | 0.94 | QPCT (0.41) | QPCTF10LTA4HKDM4EALDH1A1 | |
| SCHEMBL25254076 | 0.94 | QPCT (0.41) | QPCTF10LTA4HKDM4EALDH1A1 | |
| SCHEMBL30244951 | 0.93 | FGFR1 (0.40) | QPCTF10ABCB1KDM4EALDH1A1 | |
| SCHEMBL25257583 | 0.91 | CETP (0.37) | QPCTF10CNR1CNR2LTA4H | |
| SCHEMBL30245771 | 0.91 | CETP (0.37) | QPCTF10CNR1CNR2LTA4H | |
| SCHEMBL25250223 | 0.90 | ALDH1A1 (0.42) | LTA4HABCB1KDM4EALDH1A1HRH3 | |
| SCHEMBL30245247 | 0.90 | ALDH1A1 (0.42) | LTA4HABCB1KDM4EALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |