Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.56 |
| ▸ | KIF11 | P52732 | 3/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | VDR | P11473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25291036 | 1.00 | EGFR (0.56) | EGFRKIF11PARP14KMT2AMEN1 | |
| SCHEMBL30455337 | 0.85 | AR (0.51) | EGFRKMT2AMEN1ALOX5 | |
| SCHEMBL25255550 | 0.85 | AR (0.51) | EGFRKMT2AMEN1ALOX5 | |
| SCHEMBL18027646 | 0.75 | MEN1 (0.53) | KMT2AMEN1HTTKDM4E | |
| SCHEMBL27442487 | 0.75 | MEN1 (0.46) | EGFRKMT2AMEN1 | |
| SCHEMBL7567033 | 0.75 | CA12 (0.53) | KMT2AMEN1TP53MAPTHTT | |
| SCHEMBL20887128 | 0.74 | KIF11 (0.60) | KIF11PARP14KMT2AMEN1JAK2 | |
| SCHEMBL9490444 | 0.74 | KIF11 (0.59) | KIF11PARP14KMT2AMEN1JAK2 | |
| SCHEMBL30346387 | 0.71 | MAPT (0.59) | EGFRKIF11PARP14KMT2AMEN1 | |
| SCHEMBL8415803 | 0.71 | MAPT (0.59) | EGFRKIF11PARP14KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121238-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023121238-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |