Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP14 | P50281 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18027646 | 0.82 | MEN1 (0.53) | ALDH1A1CYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL28126564 | 0.81 | ALDH1A1 (0.52) | CA12CA2MMP2MMP9MMP8 | |
| SCHEMBL729010 | 0.80 | IDO1 (0.55) | CA12CA2MMP2MMP9MMP8 | |
| SCHEMBL32575454 | 0.80 | IDO1 (0.55) | CA12CA2MMP2MMP9MMP8 | |
| SCHEMBL7629478 | 0.80 | CYP3A4 (0.51) | CA12CA2MMP2MMP9MMP8 | |
| SCHEMBL7629487 | 0.80 | CYP3A4 (0.51) | CA12CA2MMP2MMP9MMP8 | |
| SCHEMBL30437405 | 0.78 | MEN1 (0.48) | MEN1KMT2AMAPTHTTGALR3 | |
| SCHEMBL8783600 | 0.77 | ALDH1A1 (0.57) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL11336488 | 0.77 | CA12 (0.56) | CA12CA2MMP2MMP9MMP8 | |
| SCHEMBL3232676 | 0.77 | CA12 (0.51) | CA12CA2MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358793-B | Secondary amine compound synthesized from alkyne and synthesis method thereof | 三峡大学 | 2021-03-23 | — | — | CN | disclosed |
| CN-110381955-A | For preventing and treating the pharmaceutical composition containing adenosine derivative of glaucoma | 未来制药有限公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-109906083-A | Pharmaceutical composition containing adenosine derivative for preventing and treating non-alcoholic steatohepatitis, hepatic fibrosis and liver cirrhosis | 未来制药有限公司 | 2019-06-18 | — | — | CN | disclosed |
| US-6384282-B2 | CATALYST IS REACTION PRODUCT OF GROUP 8 METAL AND LIGAND | YALE UNIVERSITY | 2002-05-07 | — | — | US | disclosed |
| US-20020016509-A1 | Transition metal-catalyzed process for addition of amines to carbon-carbon double bonds | YALE UNIVERSITY | 2002-02-07 | — | — | US | disclosed |
| CN-1089984-A | Method for producing water-proof material | WU YANQIU (CN) | 1994-07-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016509-A1 | Transition metal-catalyzed process for addition of amines to carbon-carbon double bonds | COASY, CMA1, ATIC | CA12 263/4885CA2 115/4885MMP2 4131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.