SCHEMBL2525483

SCHEMBL2525483

CC(=O)NCC(=O)N1CC(NC(=O)c2ccccc2)CC1C(N)=O

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 11/20 0.56
DPP4 P27487 3/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ANPEP P15144 6/20 0.43
PREP P48147 2/20 0.40
FAP Q12884 1/20 0.40
HPGD P15428 1/20 0.40
CARM1 Q86X55 1/20 0.40
PRMT6 Q96LA8 1/20 0.40
CHRM1 P11229 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2401942 0.91 MMP2 (0.58) MMP2DPP4ANPEPPREPFAP
SCHEMBL2527730 0.91 MMP2 (0.58) MMP2DPP4ANPEPPREPFAP
SCHEMBL14509062 0.86 MMP2 (0.50) MMP2DPP4SMN1; SMN2ANPEPCHRM1
SCHEMBL2522892 0.86 MMP2 (0.50) MMP2DPP4SMN1; SMN2ANPEPCHRM1
SCHEMBL2399929 0.86 MMP2 (0.50) MMP2DPP4SMN1; SMN2ANPEPCHRM1
SCHEMBL2523726 0.85 MMP2 (0.55) MMP2DPP4SMN1; SMN2ANPEPHPGD
SCHEMBL2399440 0.85 MMP2 (0.55) MMP2DPP4SMN1; SMN2ANPEPHPGD
SCHEMBL4967685 0.80 MMP2 (0.53) MMP2DPP4ANPEPPREPFAP
SCHEMBL2399418 0.80 MMP2 (0.53) MMP2DPP4ANPEPPREPFAP
SCHEMBL2399790 0.79 MMP2 (0.57) MMP2ANPEPHPGDCARM1PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2386539-A2 Modified lysine-mimetic compounds Zealand Pharma A/S (DK) 2011-11-16 EP claimed
US-D647202-S1 Bone marrow harvesting device WARSAW ORTHOPEDIC, INC. (US) 2011-10-18 US claimed