Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835334 | 0.80 | HTR6 (0.58) | HTR6PDE4AAGO2ALDH1A1MAPT | |
| SCHEMBL2409649 | 0.75 | TSHR (0.46) | CYP3A4CYP2C19CYP2C9LMNAKMT2A | |
| SCHEMBL7837170 | 0.73 | HTR6 (0.75) | HTR6PDE4AAGO2ALDH1A1MAPT | |
| SCHEMBL7833846 | 0.72 | HTR6 (0.54) | HTR6PDE4AAGO2ALDH1A1MAPT | |
| SCHEMBL7834630 | 0.72 | HTR6 (0.76) | HTR6PDE4AAGO2ALDH1A1MAPT | |
| SCHEMBL7832410 | 0.70 | L3MBTL1 (0.58) | HTR6PDE4AAGO2ALDH1A1MAPT | |
| SCHEMBL7836079 | 0.69 | L3MBTL1 (0.67) | HTR6PDE4AAGO2ALDH1A1MAPT | |
| SCHEMBL1136466 | 0.69 | CYP2C19 (0.64) | HTR6PDE4AAGO2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8054954 | 0.68 | CYP2C19 (0.62) | HTR6PDE4AAGO2ALDH1A1MAPT | |
| SCHEMBL26806899 | 0.68 | MAPT (0.57) | ALDH1A1MAPTKDM4ENPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2377531-A2 | Neurogenesis by modulating angiotensin | Braincells, Inc. (US) | 2011-10-19 | — | — | EP | disclosed |