SCHEMBL2525531

SCHEMBL2525531

CC(=O)N=CN(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14948894 1.00
SCHEMBL2525528 1.00
SCHEMBL28890358 0.76 CYP1A2 (0.31)
SCHEMBL27965634 0.74 ALDH1A1 (0.34)
SCHEMBL13778774 0.72 MAPT (0.30)
SCHEMBL20865493 0.71
SCHEMBL22792883 0.71
SCHEMBL22222387 0.71
SCHEMBL20048168 0.71
SCHEMBL23702708 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4430037-B1 ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF GENZYME CORP (US) 2025-10-29 EP disclosed
US-20250122186-A1 ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF GENZYME CORP (US) 2025-04-17 US disclosed
EP-4430037-A1 ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF GENZYME CORPORATION (US) 2024-09-18 EP disclosed
US-20240287070-A1 FUSED HETEROCYCLIC DERIVATIVES JOHNSON & JOHNSON (CHINA) INVESTMENT LTD. (CN) 2024-08-29 US disclosed
US-20240279227-A1 FUSED HETEROCYCLIC DERIVATIVES JANSSEN BIOTECH, INC. 2024-08-22 US disclosed
CN-118510775-A Isoxazolidines as RIPK1 inhibitors and their use 建新公司 2024-08-16 CN disclosed
CN-117881661-A Condensed heterocyclic derivative 杨森科学爱尔兰无限公司 2024-04-12 CN disclosed
EP-4347590-A1 FUSED HETEROCYCLIC DERIVATIVES Janssen Sciences Ireland Unlimited Company (IE) 2024-04-10 EP disclosed
EP-4347036-A1 FUSED HETEROCYCLIC DERIVATIVES Janssen Sciences Ireland Unlimited Company (IE) 2024-04-10 EP disclosed
US-20240109882-A1 ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF GENZYME CORP (US) 2024-04-04 US disclosed
EP-2104670-A2 NOVEL TRIAZINEDIONE DERIVATIVES AS GABA-B RECEPTOR MODULATORS Addex Pharma SA (CH) 2009-09-30 EP disclosed
EP-1948666-A1 HIV INTEGRASE INHIBITORS Bristol-Myers Squibb Company (US) 2008-07-30 EP disclosed
WO-2008056257-A2 NOVEL TRIAZINEDIONE DERIVATIVES AS GABA-B RECEPTOR MODULATORS ADDEX PHARMA S.A (CH) 2008-05-15 WO disclosed
WO-2007061714-A1 HIV INTEGRASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-05-31 WO disclosed
US-20070111984-A1 HIV integrase inhibitors BRISTOL-MYERS SQUIBB COMPANY 2007-05-17 US disclosed
EP-0837856-B1 PESTICIDAL TRIS-OXIMINO HETEROCYCLIC COMPOUNDS BAYER AG (DE) 2002-06-19 EP disclosed
EP-1184368-A1 Intermediates for pesticidal tris-oximino heterocyclic compounds BAYER AG (DE) 2002-03-06 EP disclosed
US-6150386-A PEST CONTROL, IN PARTICULAR, AS MICROBICIDES, INSECTICIDES AND ACARICIDES IN AGRICULTURE, IN HORTICULTURE AND HYGIENE SECTOR; CROP STORAGE; FUNGICIDES NOVARTIS CROP PROTECTION, INC. (US) 2000-11-21 US disclosed
EP-0837856-A1 PESTICIDAL TRIS-OXIMINO HETEROCYCLIC COMPOUNDS Novartis AG (CH) 1998-04-29 EP disclosed
WO-1997000866-A1 PESTICIDAL TRIS-OXIMINO HETEROCYCLIC COMPOUNDS NOVARTIS AG (CH) 1997-01-09 WO disclosed