Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 9/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2530529 | 0.94 | ADRB3 (0.41) | ADRB3PPARGPPARAKDM4EGAA | |
| SCHEMBL2527110 | 0.90 | ALOX15 (0.45) | PPARGPPARAKDM4ESMN1; SMN2ALOX15 | |
| SCHEMBL2523411 | 0.90 | ALOX15 (0.45) | ADRB3PPARGPPARAKDM4ESMN1; SMN2 | |
| SCHEMBL2525521 | 0.90 | PPARG (0.45) | ADRB3PPARGPPARAKDM4EGAA | |
| SCHEMBL2527446 | 0.89 | PPARG (0.42) | ADRB3PPARGPPARAKDM4EGAA | |
| SCHEMBL2528949 | 0.89 | L3MBTL1 (0.42) | ADRB3PPARGPPARAKDM4EGAA | |
| SCHEMBL2527546 | 0.89 | TDP1 (0.47) | ADRB3PPARGPPARAKDM4EGAA | |
| SCHEMBL2530994 | 0.88 | PPARG (0.41) | ADRB3PPARGPPARAKDM4EGAA | |
| SCHEMBL2526373 | 0.88 | KMT2A (0.49) | ADRB3PPARGPPARAKDM4EGAA | |
| SCHEMBL2526415 | 0.88 | KMT2A (0.49) | ADRB3PPARGPPARAALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | ADRB3 557/4885PPARG 1096/4885PPARA 381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.