Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 2/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30245596 | 1.00 | CYP11B1 (0.54) | CYP11B1CYP11B2MEN1KMT2ACHRM2 | |
| SCHEMBL25425980 | 0.91 | CYP11B1 (0.53) | CYP11B1CYP11B2MEN1KMT2ACHRM2 | |
| SCHEMBL6389607 | 0.85 | CYP11B1 (0.71) | CYP11B1CYP11B2SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29194768 | 0.80 | CYP11B1 (0.51) | CYP11B1CYP11B2PDE5ATBXAS1PDE3B | |
| SCHEMBL25426507 | 0.79 | DGAT2 (0.53) | MEN1KMT2ACHRM2SMN1; SMN2KDM4E | |
| SCHEMBL30245937 | 0.79 | DGAT2 (0.53) | MEN1KMT2ACHRM2SMN1; SMN2KDM4E | |
| SCHEMBL25426299 | 0.78 | CYP11B1 (0.47) | CYP11B1CYP11B2SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30245712 | 0.78 | CYP11B1 (0.47) | CYP11B1CYP11B2SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25427881 | 0.78 | CYP11B1 (0.46) | CYP11B1CYP11B2SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30244976 | 0.78 | CYP11B1 (0.46) | CYP11B1CYP11B2SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |