Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 8/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69432 | 0.84 | NOTUM (0.60) | NOTUMTSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL17694561 | 0.80 | NOTUM (0.78) | NOTUMTSHRALDH1A1KDM4ELMNA | |
| SCHEMBL14482401 | 0.80 | NOTUM (0.55) | NOTUMPARP1ALDH1A1KMT2AHPGD | |
| SCHEMBL16063769 | 0.78 | NOTUM (0.50) | NOTUMTSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL22312193 | 0.78 | TSHR (0.55) | NOTUMTSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL2610163 | 0.78 | NOTUM (0.75) | NOTUMTSHRALDH1A1KDM4ELMNA | |
| Acetamide SCHEMBL28274790 | 0.77 | NOTUM (0.72) | NOTUMTSHRPARP1L3MBTL1ALDH1A1 | |
| SCHEMBL3467209 | 0.76 | TSHR (0.47) | NOTUMTSHRPARP1ALDH1A1KDM4E | |
| SCHEMBL368913 | 0.75 | NOTUM (0.64) | NOTUMTSHRALDH1A1KDM4ELMNA | |
| SCHEMBL860256 | 0.75 | NOTUM (0.64) | NOTUMTSHRL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174624-A1 | CHIRAL N-(1,3,4-OXADIAZOLE-2-YL)PHENYL CARBOXYLIC ACID AMIDES AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174624-A1 | CHIRAL N-(1,3,4-OXADIAZOLE-2-YL)PHENYL CARBOXYLIC ACID AMIDES AND THEIR USE AS HERBICIDES | NAT1, NR1I3, CBR3 | NOTUM 532/4885TSHR 1066/4885PARP1 3278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.