Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25250588 | 0.83 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL28458253 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL10317449 | 0.75 | CA1 (0.46) | LMNAHSD17B10KMT2APOLBMAPT | |
| SCHEMBL16857532 | 0.75 | DPP4 (0.48) | ALDH1A1KDM4ELMNAHSD17B10KMT2A | |
| SCHEMBL16165038 | 0.75 | DPP4 (0.48) | ALDH1A1KDM4ELMNAHSD17B10KMT2A | |
| SCHEMBL16857380 | 0.75 | DPP4 (0.48) | ALDH1A1KDM4ELMNAHSD17B10KMT2A | |
| SCHEMBL2552767 | 0.75 | DPP4 (0.48) | ALDH1A1KDM4ELMNAHSD17B10KMT2A | |
| SCHEMBL16165039 | 0.75 | DPP4 (0.48) | ALDH1A1KDM4ELMNAHSD17B10KMT2A | |
| SCHEMBL28358683 | 0.74 | RECQL (0.46) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL2672977 | 0.74 | HSD17B10 (0.63) | ALDH1A1KDM4EHPGDLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4208452-A1 | QUINOLINE CGAS ANTAGONIST COMPOUNDS | Immunesensor Therapeutics, Inc. (US) | 2023-07-12 | — | — | EP | disclosed |