Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28719755 | 0.82 | KEAP1 (0.49) | HSD17B10KMT2ALMNAMEN1CHRM2 | |
| SCHEMBL16164987 | 0.82 | ADRA2C (0.62) | HSD17B10KMT2ALMNAMEN1CHRM2 | |
| SCHEMBL16857260 | 0.82 | KEAP1 (0.49) | HSD17B10KMT2ALMNAMEN1CHRM2 | |
| SCHEMBL16857387 | 0.82 | KEAP1 (0.49) | HSD17B10KMT2ALMNAMEN1CHRM2 | |
| SCHEMBL16165038 | 0.80 | DPP4 (0.48) | HSD17B10KMT2ALMNAMEN1ADRA2C | |
| SCHEMBL2552767 | 0.80 | DPP4 (0.48) | HSD17B10KMT2ALMNAMEN1ADRA2C | |
| SCHEMBL16857532 | 0.80 | DPP4 (0.48) | HSD17B10KMT2ALMNAMEN1ADRA2C | |
| SCHEMBL16857380 | 0.80 | DPP4 (0.48) | HSD17B10KMT2ALMNAMEN1ADRA2C | |
| SCHEMBL16165039 | 0.80 | DPP4 (0.48) | HSD17B10KMT2ALMNAMEN1ADRA2C | |
| SCHEMBL2672977 | 0.78 | HSD17B10 (0.63) | RECQLHSD17B10KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831584-B | Targeted drug rescue with novel compositions, combinations and methods thereof | 埃克塞瓦有限责任公司 | 2023-03-10 | — | — | CN | claimed |
| CN-110831584-A | Targeted drug rescue with novel compositions, combinations and methods thereof | 埃克塞瓦有限责任公司 | 2020-02-21 | — | — | CN | claimed |
| CN-110831584-A | Targeted drug rescue with novel compositions, combinations and methods thereof | 埃克塞瓦有限责任公司 | 2020-02-21 | — | — | CN | disclosed |